Biological Functions of the Novel Collectins CL-L1, CL-K1, and CL-P1
نویسندگان
چکیده
منابع مشابه
Biological Functions of the Novel Collectins CL-L1, CL-K1, and CL-P1
Collectins are characterized by a collagen-like sequence and a carbohydrate recognition domain and are members of the vertebrate C-type lectin superfamily. Recently, "novel collectins", different from "classical collectins" consisting of mannan-binding lectin (MBL) and surfactant proteins A and D (SP-A and SP-D), have been found by reverse genetics. These "novel collectins" consist of collectin...
متن کاملImmunolocalization of a novel collectin CL-K1 in murine tissues.
We have recently identified a novel collectin, CL-K1, that may play a role in innate immunity as a member of the collectin family. In this study using mice, we investigated the tissue distribution of CL-K1 for better understanding of its pathophysiological relevance. Real-time PCR analyses demonstrated that CL-K1 mRNA was expressed in all tissues tested. Immunohistochemical analyses demonstrate...
متن کاملAn enzyme-linked immunosorbent assay (ELISA) for quantification of human collectin 11 (CL-11, CL-K1)
Collectin 11 (CL-11), also referred to as collectin kidney 1 (CL-K1), is a pattern recognition molecule that belongs to the collectin group of proteins involved in innate immunity. It interacts with glycoconjugates on pathogen surfaces and has been found in complex with mannose-binding lectin-associated serine protease 1 (MASP-1) and/or MASP-3 in circulation. Mutation in the CL-11 gene was rece...
متن کاملOptical actinometry of Cl 2 , Cl , Cl ¿ , and Ar ¿ densities in inductively coupled Cl 2 – Ar plasmas
Optical emission ~OE! actinometry has been used to measure the absolute densities of Cl2, Cl, Cl , and Ar in a high-density inductively coupled ~ICP! Cl2 –Ar plasma at 18 mTorr as a function of the 13.56 MHz radio frequency ~rf! power and Ar fraction. The fractional dissociation of Cl2 to Cl increases with rf power, with the dissociated fraction increasing from 78% to 96% at 600 W ~10.6 W cm! a...
متن کاملGenetic Variation of COLEC10 and COLEC11 and Association with Serum Levels of Collectin Liver 1 (CL-L1) and Collectin Kidney 1 (CL-K1)
Collectin liver 1 (CL-L1, alias CL-10) and collectin kidney 1 (CL-K1, alias CL-11), encoded by the COLEC10 and COLEC11 genes, respectively, are highly homologous soluble pattern recognition molecules in the lectin pathway of complement. These proteins may be involved in anti-microbial activity and in tissue development as mutations in COLEC11 are one of the causes of the developmental defect sy...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biomedicine and Biotechnology
سال: 2012
ISSN: 1110-7243,1110-7251
DOI: 10.1155/2012/493945